Garg Lab
School of Chemistry and Biochemistry
Cystic Fibrosis associated lung microbial communities
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The microbial community residing inside the host, also termed as the 'host microbiome', interacts with each other, the host and the environment, in part, via small molecules called secondary metabolites/specialized metabolites/natural products. Shift in this microbiome can be due to the presence and absence of these small molecule natural products upon specific environmental trigger. Despite the importance of small molecules in human health and microbial ecology, our knowledge base and inventory of these small molecule effectors is limited. We know very little about the function of natural products and regulation of their production in the context of multispecies communities. Garg lab finds these small molecules using mass spectrometry, spatial metabolomics, understands how they are biosynthesized using genomics, and finds what they do using microbiology and biochemistry in microbial communities associated with human and coral diseases. Our long-term goal is to understand the role of community composition and microbiome interactions in regulation of secondary metabolism. How microbial interactions and natural product biosynthesis is affected by presence of chemical triggers such as antimicrobial compounds, and bacterial phenotypes such as quorum sensing, pigment production and others and how natural products affect multispecies interactions?
Assistant Professor
School of Chemistry and Biochemistry
Engineered Biosystems Building
Georgia Institute of Technology
Email: neha.garg (at) chemistry.gatech.edu
Office: EBB 4016
Professor Garg received Bachelors in Engineering in Biotechnology from University Institute of Technology and Masters in Science from Indian Institute of Technology, Delhi under the mentorship of Professor. Saroj Mishra. During her masters, she spent several months in Berlin, Germany while conducting research with Professor Marion Ansorge Schumacher at Technical University, Berlin as a DAAD Fellow. Garg obtained her Ph.D. in 2013 from the University of Illinois, Urbana Champaign under the direction of Professor Wilfred A. van der Donk and Professor Satish Nair. She then joined Professor Pieter C Dorrestein's research laboratory as a postdoctoral research associate at the University of California, San Diego. Garg joined the faculty at GeorgiaTech in 2017.
School of Chemistry and Biochemistry
Engineered Biosystems Building
Georgia Institute of Technology
Email: neha.garg (at) chemistry.gatech.edu
Office: EBB 4016
Professor Garg received Bachelors in Engineering in Biotechnology from University Institute of Technology and Masters in Science from Indian Institute of Technology, Delhi under the mentorship of Professor. Saroj Mishra. During her masters, she spent several months in Berlin, Germany while conducting research with Professor Marion Ansorge Schumacher at Technical University, Berlin as a DAAD Fellow. Garg obtained her Ph.D. in 2013 from the University of Illinois, Urbana Champaign under the direction of Professor Wilfred A. van der Donk and Professor Satish Nair. She then joined Professor Pieter C Dorrestein's research laboratory as a postdoctoral research associate at the University of California, San Diego. Garg joined the faculty at GeorgiaTech in 2017.